Protein purification methods to reduce acidic species
US9957318B2 · kind B2 · utility
9Cited by
243References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 9, 2016 |
| Grant date | May 1, 2018 |
| Priority date | — |
| Expiry date | Sep 16, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/21
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the amount of charge variants, aggregates, and fragments of a protein of interest, as well as host cell proteins, present in purified preparations by applying particular chromatography conditions during such protein purification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.