Method for enzymatic treatment of tissue products
US9957477B2 · kind B2 · utility
11Cited by
16References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 8, 2015 |
| Grant date | May 1, 2018 |
| Priority date | — |
| Expiry date | Dec 8, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/40
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating a tissue matrix with a proteolytic enzyme to produce a desired pliability of the tissue matrix and/or to control the immunogenicity of the tissue matrix. The methods can also comprise performing an assay to determine if contacting the at least one collagen-containing tissue matrix with a proteolytic enzyme has altered the at least one collagen-containing tissue matrix to reduce a human immune response to the tissue matrix.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.