Cardiomyocyte production
US9957482B2 · kind B2 · utility
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4References
14Claims
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Key dates
| Filing date | Mar 23, 2015 |
| Grant date | May 1, 2018 |
| Priority date | — |
| Expiry date | Mar 23, 2035 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E60/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.