Patent · US Active

Multiloop engineered heart muscle tissue

US9957483B2 · kind B2 · utility

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10Claims

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Inventors

Wolfram-Hubertus Zimmermann · Göttingen, DE
Thomas Eschenhagen · Hamburg, DE

Key dates

Filing date	Apr 9, 2015
Grant date	May 1, 2018
Priority date	—
Expiry date	Jul 16, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2506/02
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention is directed to a method for the preparation of a multiring engineered heart tissue construct suitable for use in cardiac tissue augmentation and/or replacement therapy. The invention further refers to multiring EHT constructs which comprise at least two force-generating engineered heart tissue rings fused with each other and a device for preparing the same. Finally, the invention relates to force-generating engineered heart tissue rings derived from human cells and their use in drug screening and target validation assays.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.