Patent · US Active

Methods for detecting CpG methylation and for diagnosing cancer

US9957575B2 · kind B2 · utility

1Cited by

0References

14Claims

0Family size

Assignee

EPIGENOMICS AG · DE

Inventors

Denise KOTTWITZ · Berlin, DE
Jörn LEWIN · Berlin, DE
Anne Schlegel · Mainz, DE
Reimo Tetzner · Berlin, DE

Key dates

Filing date	Feb 17, 2017
Grant date	May 1, 2018
Priority date	—
Expiry date	Feb 17, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/158
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to the field of pharmacogenomics and in particular to detecting the presence or absence of hypermethylated DNA. The detection of CpG methylation in marker DNA is useful for the diagnosis of cancers and the invention provides improved methods for this purpose. These improved methods allow in particular for a more sensitive detection of methylated marker DNA with high backgrounds of unmethylated marker DNA.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.