Stabilized assembled nanostructures for delivery of encapsulated agents
US9962339B2 · kind B2 · utility
6Cited by
3References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 7, 2016 |
| Grant date | May 8, 2018 |
| Priority date | — |
| Expiry date | Oct 7, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-covalently assembled hydrogel or organo-gel composition with serum stability is described. Low molecular weight (<2,500 Da), generally regarded as safe (GRAS), materials assemble in the presence of a stabilizing agent at an appropriate molar percentage, forming hydrogel or organo-gel with nanostructures that resist disassembly or destabilization in serum for an extended period of time. The composition is used to deliver one or more therapeutic, prophylactic, or diagnostic agents, allowing for controlled release in response to biological stimuli such as enzymes and a greatly improved dosing efficacy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.