Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof
US9962366B2 · kind B2 · utility
7Cited by
2References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 10, 2015 |
| Grant date | May 8, 2018 |
| Priority date | — |
| Expiry date | Mar 10, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/80
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are methods, compounds, and compositions useful for increasing autophagy and promoting longevity. The methods, compounds, and compositions relate to urolithins and urolithin precursors and use thereof. Certain urolithins are represented by Formula I, while certain urolithin precursors are represented by Formula IV. The urolithin may be urolithin A, urolithin B, urolithin C, or urolithin D. The urolithin precursor may be ellagic acid or an ellagitannin. The methods include in vivo, ex vivo, and in vitro uses of the compounds and compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.