Inhibitors of the FKBP51 protein from a high-throughput drug screen and methods of use
US9962379B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Jul 13, 2016 |
| Grant date | May 8, 2018 |
| Priority date | — |
| Expiry date | Jul 13, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/99
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or animal. In one embodiment, a person or animal in need of treatment is administered one or more compounds or drugs, or a composition comprising the one or more compounds or drugs, that inhibit FKBP51 activity or function. The subject invention also concerns a method for inhibiting activity of the FKBP51 protein in a cell. The subject invention also concerns methods of screening for compounds or drugs that inhibit the FKBP51 protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.