Compositions and methods of use
US9962412B2 · kind B2 · utility
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21Claims
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Assignee
Inventor
Key dates
| Filing date | Apr 29, 2013 |
| Grant date | May 8, 2018 |
| Priority date | — |
| Expiry date | Apr 29, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/145
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a derivative bacterial strain of an avirulent, non-pathogenic Clostridium ghonii that is capable of arresting the growth of, regressing or destroying one or more solid tumors. The present invention further relates to a composition comprising the derivative bacterial strain for targeted lysis of solid tumors. The present invention further relates to methods of producing derivative strains of C. ghonii by serial culturing in tumor bearing animals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.