Processing microtitre plates for covalent immobilization chemistries
US9962676B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Mar 31, 2015 |
| Grant date | May 8, 2018 |
| Priority date | — |
| Expiry date | Mar 31, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2325/06
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein is a method of: treating an organic polymer with an electron beam-generated plasma; exposing the treated polymer to air or an oxygen- and hydrogen-containing gas, generating hydroxyl groups on the surface of the polymer; reacting the surface with an organosilane compound having a chloro, fluoro, or alkoxy group and a functional or reactive group that is less reactive with the surface than the chloro, fluoro, or alkoxy group; and covalently immobilizing a biomolecule to the functional or reactive group or a reaction product thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.