Macrocyclic compounds

US9963464B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Ulrich Lücking · Berlin, DE
• Pierre Wasnaire · Mülheim an der Ruhr, DE
• Arne Scholz · Berlin, DE
• Philip Lienau · Berlin, DE
• Gerhard Siemeister · Berlin, DE
• Christian Stegmann · Berlin, DE
• Ulf Bömer · Glienicke, DE
• Kunzeng Zheng · Shanghai, CN
• Ping Gao · Portage, US
• Gang Chen · Sammamish, US
• Jiajun Xi · Shanghai, CN

Key dates

• Filing date: Apr 8, 2015
• Grant date: May 8, 2018
• Expiry date: Apr 8, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel macrocyclic compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).