FAD2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks

US9963711B2 · kind B2 · utility

Assignees

• Sangamo Therapeutics, Inc. · US
• DOW AGROSCIENCES LLC · US

Inventors

• Noel Cogan · Melbourne, AU
• John White Forster · Whittlesea, AU
• Matthew Hayden · Melbourne, AU
• Tim Sawbridge · Melbourne, AU
• German Spangenberg · Melbourne, AU
• Steven R. Webb · Westfield, US
• Manju Gupta · Carmel, US
• William M. Ainley · Carmel, US
• Matthew J. Henry · Indianapolis, US
• Jeffrey C. Miller · Pleasanton, US
• Dmitry Y. Guschin · Seojong-myeon, KR

Key dates

• Filing date: Sep 5, 2013
• Grant date: May 8, 2018
• Expiry date: Aug 20, 2035

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A40/146
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A method of gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a cell, to generate a break in the FAD2 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.