Method of screening gene for 1,4-BDO production
US9963721B2 · kind B2 · utility
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Key dates
| Filing date | Aug 22, 2014 |
| Grant date | May 8, 2018 |
| Priority date | — |
| Expiry date | Sep 29, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/91045
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided is a screening method of discovering genes capable of increasing 1,4-BDO production on the basis of proteomics data. Over-expression of proteins screened by the method, NCgl0630 (citrate synthase) and NCgl2145 (hypothetical protein), increase 1,4-BDO productivity. The method may lead to screening of a protein associated with 1,4-BDO productivity, thereby increasing 1,4-BDO productivity, and thus, the method may be recognized as being industrially applicable.
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