Noise reduction methods for nucleic acid and macromolecule sequencing
US9965586B2 · kind B2 · utility
0Cited by
0References
15Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Mar 20, 2015 |
| Grant date | May 8, 2018 |
| Priority date | — |
| Expiry date | May 24, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B30/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Methods, systems, and devices are disclosed for processing macromolecule sequencing data with substantial noise reduction. In one aspect, a method for reducing noise in a sequential measurement of a macromolecule comprising serial subunits includes cross-correlating multiple measured signals of a physical property of subunits of interest of the macromolecule, the multiple measured signals including the time data associated with the measurement of the signal, to remove or at least reduce signal noise that is not in the same frequency and in phase with the systematic signal contribution of the measured signals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.