2-(2-methylamino-pyrimidin-4-yl)-1h-indole-5-carboxylic acid [(S)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl]-amide for use in the treatment of pain associated to osteoarthritis

US9968605B2 · kind B2 · utility

Assignee

• Sanofi · FR

Inventors

• Tobias Paehler · Frankfurt am Main, DE
• Klaus Flechsenhar · Frankfurt am Main, DE
• Kirsten Grothe · Frankfurt am Main, DE
• Martin Lunnon · Paris, FR
• Christelle Jan · Paris, FR

Key dates

• Filing date: Jun 30, 2015
• Grant date: May 15, 2018
• Expiry date: Jun 30, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

2-(2-methylamino-pyrimidin-4-yl)-1H-indole-5-carboxylic acid [(S)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl]-amide for use in the treatment of pain associated with osteoarthritis in the knee.