Solid forms comprising 4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one and a coformer, compositions and methods of use thereof

US9968627B2 · kind B2 · utility

Assignee

• CELGENE CORPORATION · US

Inventors

• G. Patrick Stahly · Baton Rouge, US
• David Jonaitis · Lafayette, US
• Ho-Wah Hui · Berkeley Heights, US
• Kevin J. Klopfer · Flemington, US

Key dates

• Filing date: Mar 25, 2014
• Grant date: May 15, 2018
• Expiry date: Jun 1, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/7064
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are solid forms comprising (a) 4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one and (b) a coformer. Pharmaceutical compositions comprising the solid forms (e.g., cocrystals) and methods for treating, preventing and managing various disorders are also disclosed.