Polypeptide hydrogel and method for producing same
US9968682B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 18, 2014 |
| Grant date | May 15, 2018 |
| Priority date | — |
| Expiry date | May 24, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A polypeptide hydrogel of the present invention is a hydrogel of a polypeptide derived from spider silk proteins, and has a moisture content of 85.0 to 99.9 mass % based on 100 mass % of the polypeptide hydrogel. A method for producing the hydrogel includes: a solution production step in which a polypeptide derived from spider silk proteins is dissolved in at least one dissolving solvent selected from the group consisting of: (A) dimethyl sulfoxide; (B) dimethyl sulfoxide with an inorganic salt; and (C) N, N-dimethylformamide with an inorganic salt, so as to obtain a solution of the polypeptide; and a substitution step in which the solution produced in the solution production step is substituted with a water-soluble solvent. Thus, the present invention provides a polypeptide hydrogel having excellent water retentivity and a polypeptide hydrogel suitable for application to a living body.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.