Patent · US Active

Histone acetyltransferase modulators and uses thereof

US9969677B2 · kind B2 · utility

1Cited by

12References

18Claims

0Family size

Assignee

The Trustees of Columbia University in the City of New York · US

Inventors

Yitshak Francis · New York, US
Mauro Fa · New York, US
Ottavio Arancio · New York, US
Jole FIORITO · Floral Park, US
Shixian Deng · White Plains, US
Donald W. Landry · New York, US
Michal LUZAC · New York, US
Yan Feng · Chengdu, CN

Key dates

Filing date	Dec 22, 2011
Grant date	May 15, 2018
Priority date	—
Expiry date	Apr 12, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D295/088
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.