Substituted 2-hydrogen-pyrazole derivative serving as anticancer drug

US9969719B2 · kind B2 · utility

Assignees

• Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · CN
• Medshine Discovery Inc. · CN

Inventors

• Charles Z. Ding · San Mateo, US
• Shuhui CHEN · Shanghai, CN
• Baoping Zhao · Shanghai, CN
• Zhaobing Xu · Shanghai, CN
• Yingchun Liu · Shanghai, CN
• Ruibin Lin · Shanghai, CN
• Fei Wang · Beijing, CN
• Jian Li · Shanghai, CN

Key dates

• Filing date: Mar 10, 2016
• Grant date: May 15, 2018
• Expiry date: Mar 10, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed is a substituted 2H-pyrazole derivative serving as a selective CDK4/6 inhibitor. Specifically, disclosed is a compound of formula (I) or a pharmaceutically acceptable salt thereof which serves as a selective CDK4/6 inhibitor.