DNA-cell conjugates

US9969970B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Shih-Chia Hsiao · Oakland, US
• Matthew B. Francis · Berkeley, US
• Carolyn R. Bertozzi · Berkeley, US
• Richard A. Mathies · Moraga, US
• Ravi Chandra · Newton, US
• Erik Douglas · Oakland, US
• Amy Twite · Berkeley, US
• Nicholas Toriello · Redwood City, US
• Hiroaki Onoe · Tokyo, JP

Key dates

• Filing date: Mar 1, 2016
• Grant date: May 15, 2018
• Expiry date: Mar 1, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/6901
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The modified cells can be linked to a substrate surface and used in assay or bioreactors.