Compositions of adenosine deaminase-2 (ADA2), variants thereof and methods of using same
US9969998B2 · kind B2 · utility
1Cited by
154References
43Claims
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Key dates
| Filing date | Apr 8, 2016 |
| Grant date | May 15, 2018 |
| Priority date | — |
| Expiry date | May 14, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are variant adenosine deaminase 2 (ADA2) proteins, conjugates thereof and compositions containing the proteins and/or conjugates. Also provided are methods and uses of the ADA2 proteins or conjugates for treating diseases and conditions, such as a tumor or cancer, and in particular any disease or condition associated with elevated adenosine or other associated marker.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.