Targeted genomic modification with partially single-stranded donor molecules
US9970028B2 · kind B2 · utility
8Cited by
28References
14Claims
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Key dates
| Filing date | Jan 7, 2016 |
| Grant date | May 15, 2018 |
| Priority date | — |
| Expiry date | Mar 21, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/81
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.