Engineering DNA assembly in vivo and methods of making and using the reverse transcriptase technology
US9970040B2 · kind B2 · utility
3Cited by
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15Claims
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Key dates
| Filing date | Sep 26, 2014 |
| Grant date | May 15, 2018 |
| Priority date | — |
| Expiry date | Sep 26, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/1276
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Cells that can synthesize oligonucleotides in vivo to produce a nucleic acid nanostructure are described. Methods for producing oligonucleotide nanostructures for use in regulating gene expression and altering biological pathways are provided. Methods of performing multiplex automated genome editing (MAGE) are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.