Quantitative assessment for cap efficiency of messenger RNA
US9970047B2 · kind B2 · utility
12Cited by
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15Claims
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Key dates
| Filing date | Mar 14, 2014 |
| Grant date | May 15, 2018 |
| Priority date | — |
| Expiry date | May 5, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y113/12007
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides, among other things, methods of quantitating mRNA capping efficiency, particularly for mRNA synthesized in vitro. In some embodiments, the methods comprise chromatographic methods of quantifying capping efficiency and methylation status of the caps.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.