Methods for detecting symmetrical dimethylarginine
US9970927B2 · kind B2 · utility
7Cited by
4References
75Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 28, 2014 |
| Grant date | May 15, 2018 |
| Priority date | — |
| Expiry date | Aug 20, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6812
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Method of detecting Symmetrical dimethyl arginine (SDMA) in biological samples. SDMA analogs for generating anti-SDMA antibodies having little or no cross-reactivity with asymmetrical dimethyl arginine, arginine, and monomethylarginine. The analogs have a protected or free thiol (—SH) group or hydroxyl (—OH) group that allow them to be linked to a suitable conjugation target which can be, for example, a protein containing molecule of a label. The anti-SDMA antibodies can be used in diagnostic immunoassay for the diagnosis of SDMA associated disorders and/or diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.