Methods and compositions for generating an immune response by inducing CD40 and pattern recognition receptor adapters
US9976122B2 · kind B2 · utility
4Cited by
41References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 21, 2016 |
| Grant date | May 22, 2018 |
| Priority date | — |
| Expiry date | Jul 21, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/10343
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing an inducible pattern recognition receptor adapter, or adapter fragment, and CD40 activity. Also provided are nucleic acid compositions comprising sequences coding for chimeric proteins that include an inducible CD40 peptide and an inducible pattern recognition receptor adapter or adapter fragment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.