Patent · US Active

Isothermal nucleic acid amplification reactor with integrated solid state membrane

US9976176B2 · kind B2 · utility

8Cited by

2References

11Claims

0Family size

Assignees

The Trustees of the University of Pennsylvania · US
NEW YORK UNIVERSITY · US

Inventors

Haim H. Bau · Swarthmore, US
William R. Abrams · Yeadon, US
Eran Geva · Brooklyn, US
Michael G. Mauk · Wilmington, US
Changchun Liu · Sunnyvale, US
Daniel Malamud · New York, US
Xianbo Qiu · Beijing, CN

Key dates

Filing date	Sep 8, 2016
Grant date	May 22, 2018
Priority date	—
Expiry date	Sep 8, 2036

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01L2400/065
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

Provided are devices adapted to isolate, amplify, and detect nucleic acids that may be present in a biological sample. The devices can, in some embodiments, isolate, amplify, and detect nucleic acid in a single chamber. In other embodiments, the devices are adapted to isolate and amplify nucleic acids in a reaction chamber, after which the nucleic acids may be communicated to a pervious medium—such as a lateral flow strip—where the user may label and detect the nucleic acids.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.