Staggered chromatography mass spectrometry
US9976995B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 12, 2015 |
| Grant date | May 22, 2018 |
| Priority date | — |
| Expiry date | Jun 12, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/461
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An analytical instrument is disclosed comprising a liquid chromatography system comprising a first column, a chromatographic delay line and a splitter arranged and adapted in a mode of operation to split eluent from the first column into a first portion of eluent and a second portion of eluent. The instrument further comprises a first device. The liquid chromatography system is arranged and adapted in the mode of operation: (i) to pass the first portion of eluent from the splitter to the first device such that a first part of the first portion of eluent arrives at the first device at a first time ti and a second part of the first portion of eluent arrives at the first device at a second time t2. The system is further arranged and adapted: (ii) to pass the second portion of eluent from the splitter through the chromatographic delay line to the first device such that the passage of the second portion of eluent from the splitter to the first device is delayed relative to the passage of the first portion of eluent from the splitter to the first device, and such that a first part of the second portion of eluent arrives at the first device at a third time t3, where t1<t3<t2. The analytic…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.