Systems and methods for detecting molecular interactions using magnetic beads
US9977015B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 15, 2013 |
| Grant date | May 22, 2018 |
| Priority date | — |
| Expiry date | Feb 2, 2035 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L3/502761
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Systems and methods are provided for detecting or measuring binding affinity between different compositions. The methods include contacting one or more magnetic beads having a surface including a first composition with a substrate having a surface including a second composition; applying a rotating magnetic field to the one or more magnetic beads effective to cause the one or more magnetic beads to move across the surface of the substrate; measuring the movement of the one or more magnetic beads across the substrate surface to determine a translational velocity; and determining a binding affinity between the first and second compositions from the translational velocity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.