Patent · US Active

Preparation of and formulation comprising a MEK inhibitor

US9980944B2 · kind B2 · utility

2Cited by
12References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 28, 2017
Grant dateMay 29, 2018
Priority date
Expiry dateFeb 28, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to processes for preparing 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxyethyoxy)-amide, processes for preparing crystallized 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxyethyoxy)-amide, and intermediates useful therefore. Also provided herein are pharmaceutical compositions comprising this crystallized compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.