Modified hyaluronic acid polymer compositions and related methods
US9980977B2 · kind B2 · utility
1Cited by
28References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 13, 2016 |
| Grant date | May 29, 2018 |
| Priority date | — |
| Expiry date | Sep 13, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2305/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application provides compositions comprising hyaluronic acid having low levels of functional group modification, mixtures formed by controlled reaction of such lightly modified hyaluronic acid with suitable difunctional or multi-functional crosslinkers, and hydrogel precursor compositions and the resulting hydrogels. The compositions are lightly cross-linked and possess low pro-inflammatory properties when injected in vivo, and can be used as, for example, medical devices, biomedical adhesives and sealants, and for localized delivery of bioactive agents, among other uses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.