Compositions, comprising improved Il-12 genetic constructs and vaccines, immunotherapeutics and methods of using the same
US9981036B2 · kind B2 · utility
6Cited by
8References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 2016 |
| Grant date | May 29, 2018 |
| Priority date | — |
| Expiry date | Feb 26, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2730/10171
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Nucleic acid molecules and compositions comprising: a nucleic acid sequence that encodes IL-12 p35 subunit or a functional fragment thereof and/or a nucleic acid sequence that encodes IL 12 p40 subunit or a functional fragment thereof, are disclosed. The nucleic acid molecules and compositions further comprising a nucleic acid sequence that encodes an immunogen are also disclosed. Method of modulating immune response and methods of inducing an immune response against an immunogen are disclosed. Therapeutic and prophylactic vaccination methods are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.