Photoswitchable HDAC inhibitors
US9981038B2 · kind B2 · utility
2Cited by
6References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 13, 2014 |
| Grant date | May 29, 2018 |
| Priority date | — |
| Expiry date | Mar 13, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to photoswitchable inhibitors of histone deacetylases and methods of using the same. Provided herein are inhibitors of HDAC having photoswitchable modulators of protein function with short thermal relaxation kinetics. The compounds are diazo compounds including a substituted or unsubstituted aryl or heteroaryl ring, wherein at least one of the rings is substituted with one or more HDAC targeting elements.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.