KDM1A inhibitors for the treatment of disease
US9981922B2 · kind B2 · utility
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Key dates
| Filing date | Feb 12, 2016 |
| Grant date | May 29, 2018 |
| Priority date | — |
| Expiry date | Feb 12, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDM1A, methods of increasing gamma globin gene expression, and methods to induce differentiation of cancer cells in a human or animal subject are also provided for the treatment of diseases such as acute myelogenous leukemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.