Enzyme-specific fluorescent compound capable of being retained in cells
US9981934B2 · kind B2 · utility
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2References
20Claims
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Assignee
Inventors
Key dates
| Filing date | May 13, 2015 |
| Grant date | May 29, 2018 |
| Priority date | — |
| Expiry date | May 13, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/938
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Provided is an enzyme-specific fluorescent compound capable of being retained in cells, which can emit fluorescence specifically in a target cell, particularly a cell capable of expressing a reporter enzyme such as β-galactosidase, and can covalently bind to a protein in the cell to exhibit an excellent property of being retained in the cell. The fluorescent compound comprises a compound represented by formula (I′) or a salt thereof. In formula (I′), A, X, Y and R1 to R9 are as described in claim 1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.