Synthesis of imidazo[1,2-a]pyrazin-4-ium salts for the synthesis of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof
US9981967B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Nov 13, 2013 |
| Grant date | May 29, 2018 |
| Priority date | — |
| Expiry date | Nov 13, 2033 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2231/72
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention embodiments relate to a compound with formula (V′)The invention also relates in certain embodiments to the synthesis method for compound (V′) and its use for the preparation of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof, particularly compounds with formula (I)The invention also relates in certain embodiments to metallic complexes comprising a ligand with formula (I) and a metal and their use for imaging.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.