Patent · US Active

Amatoxin derivatives

US9982018B2 · kind B2 · utility

0Cited by

0References

24Claims

0Family size

Assignee

Heidelberg Pharma GmbH · DE

Inventors

Christoph Müller · Birkenau, DE
Jan Anderl · Herchenrode, DE
Werner Simon · Seeheim-Jugenheim, DE
Christian Lutz · Kassel, DE
Torsten Hechler · Ladenburg, DE

Key dates

Filing date	Mar 10, 2014
Grant date	May 29, 2018
Priority date	—
Expiry date	Mar 10, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K16/32
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to tumor therapy. In one aspect, the present invention relates to conjugates of an amatoxin and a target-binding moiety, e.g. an antibody, connected by certain linkages, which are useful in the treatment of cancer and other disorders and diseases. In a further aspect the invention relates to pharmaceutical compositions comprising such conjugates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.