Antibodies to ticagrelor and methods of use

US9982061B2 · kind B2 · utility

Assignee

• MedImmune Limited · US

Inventors

• Andrew Buchanan · Cambridge, GB
• Sven Nylander · Gately Drive, SE
• Mark Penney · Cambridge, GB
• Philip Newton · Cambridge, GB
• Feenagh Keyes · Cambridge, GB
• Tord Inghardt · Gately Drive, SE

Key dates

• Filing date: Sep 30, 2015
• Grant date: May 29, 2018
• Expiry date: Apr 3, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure generally provides antibodies and antigen binding fragments of antibodies that bind ticagrelor and metabolites of ticagrelor. The disclosure also provides compositions comprising the antibodies, nucleic acid molecules encoding the antibodies, methods of treating a patient comprising administering the antibodies, and methods of making and using the antibodies.