Methods for reprogramming differentiated non-cardiac cells into cardiomyocytes

US9982231B2 · kind B2 · utility

Assignee

• The J. David Gladstone Institute, a testamentary trust established under the Will of J. David Gladstone · US

Inventors

• Nan Cao · Beijing, CN
• Sheng Ding · San Diego, US

Key dates

• Filing date: Mar 10, 2016
• Grant date: May 29, 2018
• Expiry date: Mar 10, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2506/1307
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compositions and methods are described herein for chemically inducing cells to change their differentiation state and become cardiac progenitor cells or cardiomyocytes.