Device and a method for imaging-guided photothermal laser therapy for cancer treatment
US9987089B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 13, 2015 |
| Grant date | Jun 5, 2018 |
| Priority date | — |
| Expiry date | Feb 7, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2018/2261
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
This invention relates to a device and a method for monitoring and optimizing photothermal therapy, using a high-power continuous-wave laser beam and a pulsed laser beam, both transmitted through a single soft, multi-mode optical fiber with a diffuse active tip, to interstitially irradiate the target tissue at the same time. The continuous-wave laser light induces photothermal effect and increases tissue temperature and the pulsed laser light produces a photoacoustic signal. The photoacoustic signal intensity is used to monitor the temperature changes in the target tissue and to guide the irradiation of the high-power laser to optimize the photothermal effect by adjusting the light intensity and irradiation time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.