Factor XII inhibitors for the administration with medical procedures comprising contact with artificial surfaces

US9987328B2 · kind B2 · utility

Assignee

• CSL Behring AG · DE

Inventors

• Stefan Zeitler · Reifenthal, DE
• Marc Nolte · Marburg, DE
• Stefan Schulte · Marburg, DE
• Gerhard Dickneite · Marburg, DE
• Ingo Pragst · Marburg, DE

Key dates

• Filing date: Apr 28, 2016
• Grant date: Jun 5, 2018
• Expiry date: Apr 28, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/76
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An inhibitor of FXII/FXIIa for the prevention of the formation and/or stabilization of thrombi during and/or after a medical procedure performed on a human or animal subject comprising contacting blood of said human or animal subject with artificial surfaces, wherein said inhibitor of FXII/FXIIa is administered before and/or during and/or after said medical procedure.