Patent · US Active

Aniline derivative, pharmaceutical composition containing same, and use thereof

US9988350B2 · kind B2 · utility

0Cited by
6References
19Claims
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Key dates

Filing dateJul 26, 2017
Grant dateJun 5, 2018
Priority date
Expiry dateJul 26, 2037

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides a compound represented by the general formula (I): in the formula, R1, R2 and R3 are each a hydrogen atom, a halogen atom, a C1-6 alkyl group, a halo C1-6 alkyl group or the like, R4 is a C1-6 alkyl group or the like, R5 is a C1-6 alkyl group or the like, R6 is a C1-6 alkyl group or the like, R7 is a hydrogen atom, a halogen atom, a C1-6 alkyl group or the like, R8 is a halogen atom, a C1-6 alkyl group, a halo C1-6 alkyl group, a C1-6 alkoxy group or the like, and R9 is a hydrogen atom or a C1-6 alkyl group, or a pharmaceutically acceptable salt thereof. The compounds of the present invention have an excellent S1P1 receptor antagonistic activity and therefore are useful as an agent for the treatment or prevention of autoimmune diseases and the like.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.