Patent · US Active

Benzisoxazole derivative salt

US9988370B2 · kind B2 · utility

0Cited by

1References

20Claims

0Family size

Assignee

RaQualia Pharma Inc. · US

Inventors

Toyoharu Numata · Ebeye, US
Masaki Sudo · Ebeye, US
Xufeng Sun · Shenyang, CN

Key dates

Filing date	May 20, 2015
Grant date	Jun 5, 2018
Priority date	—
Expiry date	May 20, 2035

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Salts of 4-{[4-({[4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazol-3-yl]oxy}methyl)piperidin-1-yl]methyl}tetrahydro-2H-pyran-4-carboxylic acid are disclosed. More particularly, salt forms (HCl-salt, HBr-salt, p-toluenesulfonate salt and ethanedisulfonate salt) are disclosed. Furthermore, processes for the preparation of such salt forms, compositions containing such salt forms, and uses of such salt forms are disclosed. A method of treating disease conditions mediated by 5-HT4 receptor activity includes administering an effective amount of such salt forms to an animal, including a human, in need of such treatment.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.