Patent · US Active

Pegylated bioactive peptides and uses thereof

US9988428B2 · kind B2 · utility

0Cited by
23References
20Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 18, 2017
Grant dateJun 5, 2018
Priority date
Expiry dateApr 18, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K14/60
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Described herein are bioactive peptides that are modified at one or more positions with a PEG moiety. An example of such a PEGylated bioactive peptide is a GHRH analog that is modified at one or more positions with a PEG moiety. Also described are pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising such analogs or salts thereof, as well as methods, kits and uses thereof, for example for inducing or stimulating growth hormone secretion in a subject and for diagnosing, preventing or treating GH-deficient conditions in a subject.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.