Patent · US Active

Anti-HIV dual specificity antibodies and methods of HIV treatment

US9988438B2 · kind B2 · utility

0Cited by

0References

19Claims

0Family size

Assignee

BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE · US

Inventors

Seth Pincus · New Orleans, US
Ryan Craig · Naas, IE

Key dates

Filing date	Jul 23, 2014
Grant date	Jun 5, 2018
Priority date	—
Expiry date	Jul 23, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/76
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Dual variable domain immunoglobulins (DVD Igs) are provided capable of tetravalent binding to bispecific sites of the human immunodeficiency virus (HIV). The DVD Igs may be asymmetric and may have more variable domains on either the light chain or the heavy chain of the Igs. The DVD Igs may have specificity for gp41 and gp120. Therapies are provided using DVD Igs to neutralize HIV viral loads.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.