Microfluidic cartridge

US9988676B2 · kind B2 · utility

Assignee

• LEIDOS INNOVATIONS TECHNOLOGY, INC. · US

Inventors

• Michael Edward EGAN · Bothell, US
• Brian Root · Charlottesville, US
• Orion N. Scott · Charlottesville, US
• Douglas J. South · Rockville, US
• Joan Bienvenue · Fredericksburg, US
• Paul Kinnon · Solana Beach, US
• James P. Landers · Charlottesville, US
• David Saul · Auckland, NZ
• An-Chi Tsuei · Charlottesville, US
• Jason Hayes · Melbourne, AU
• Matthew Springer · Melbourne, AU
• Matthew Daniel Solomon · Melbourne, AU
• Peter Van Ruijven · Melbourne, AU

Key dates

• Filing date: Jun 19, 2015
• Grant date: Jun 5, 2018
• Expiry date: Oct 18, 2035

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2400/088
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge.