Use of alginate compositions in preventing or reducing liver damage caused by a hepatotoxic agent

US9993497B2 · kind B2 · utility

Assignees

• HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. · IL
• B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY · IL

Inventors

• Smadar Cohen · Beer Sheva, IL
• Yaron Ilan · Kfar Tavor, IL
• Eyal Shteyer · Mevaseret Tsiyon, IL
• Ami Ben-Ya'acov · Jerusalem, IL

Key dates

• Filing date: Dec 30, 2013
• Grant date: Jun 12, 2018
• Expiry date: Mar 3, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P29/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are compositions, methods and uses utilizing alginate compositions, for treating, preventing and/or reducing liver damage induced by a hepatotoxic agent, and for treating a medical condition treatable by a hepatotoxic agent, in which an alginate composition is administered prior to, concomitant with, or shortly after exposure to a hepatotoxic agent. Also disclosed are pharmaceutical compositions comprising a hepatotoxic agent and an alginate composition and uses thereof for treating medical conditions treatable by the hepatotoxic agent.