Tricyclic quinoline and quinoxaline derivatives

US9994568B2 · kind B2 · utility

Assignee

• Abb Vie Deutschland Gmbh & Co. KG · DE

Inventors

• Hannes Fiepko KOOLMAN · North Chicago, US
• Wilfried Braje · Ludwigshafen, DE
• Helmut Mack · Ludwigshafen, DE
• Andreas Haupt · Ludwigshafen, DE
• Ana-Lucia Relo · Ludwigshafen, DE
• Karla Drescher · Ludwigshafen, DE
• Margaretha Henrica Maria Bakker · Ludwigshafen, DE
• Viktor Lakics · Budapest, HU
• Carolin Hoft · Ludwigshafen, DE

Key dates

• Filing date: Sep 29, 2015
• Grant date: Jun 12, 2018
• Expiry date: Sep 29, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to tricyclic quinoline and quinoxaline derivatives, to a pharmaceutical composition containing such compounds, to their use as modulators, especially agonists or partial agonists, of the 5-HT2C receptor, their use for preparing a medicament for the prevention or treatment of conditions and disorders which respond to the modulation of 5-HT2C receptor, and to a method for preventing or treating conditions and disorders which respond to the modulation of 5-HT2C receptor.