Patent · US Active

Separation method for fucosylated antibodies

US9994610B2 · kind B2 · utility

0Cited by

0References

21Claims

0Family size

Assignee

Roche Glycart AG · CH

Inventors

Anne Freimoser-Grundschober · Bellinzona, CH
Christiane Jaeger · Wallisellen, CH
Peter Sondermann · Stockdorf, DE
Pablo Umana · Wollerau, CH

Key dates

Filing date	Oct 16, 2012
Grant date	Jun 12, 2018
Priority date	—
Expiry date	Dec 20, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/41
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to a method for the separation of antibodies, specifically antibodies having different degrees of fucosylation. The method is based on binding affinity of antibodies to Fc receptors. The invention further relates to the use of Fc receptors for the separation of antibodies having different degrees of fucosylation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.