Methods and compositions for improving efficiency of nucleic acids amplification reactions
US9994887B2 · kind B2 · utility
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5References
7Claims
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Key dates
| Filing date | Sep 10, 2014 |
| Grant date | Jun 12, 2018 |
| Priority date | — |
| Expiry date | Sep 10, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/80
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid polymerases that show increased processivity over wild type polymerases as well as decreased exonucleases activity. The invention also encompasses methods, compositions and kits for conducting nucleic acid synthesis and amplification reactions in which non-specific amplification of primers is reduced.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.